Brief Information of the Compound and Protein
Compound Name
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-1-morpholin-4-ylethanone
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PubChem ID
CID: 145976113
Canonical SMILES
OC(c1ccc2N(CC(CC(=O)N3CCOCC3)Sc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F
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Compound Formula C23H21F7N2O5S2
Compound Structure
Protein Name
Oxysterols receptor LXR-alpha
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
Q13133
Gene Name
NR1H3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 980 nM
   TI
   LI
   LO
   TS