Brief Information of the Compound and Protein
Compound Name
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide
    Show/Hide
PubChem ID
CID: 145965870
Canonical SMILES
OC(c1ccc2N(CC(CC(=O)Nc3nncs3)Sc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F
    Show/Hide
Compound Formula C21H15F7N4O4S3
Compound Structure
Protein Name
Nuclear receptor subfamily 1 group I member 2
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group I
>
Nuclear hormone receptor subfamily 1 group I member 2
Uniprot ID
O75469
Gene Name
NR1I2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 254 nM
   TI
   LI
   LO
   TS