Brief Information of the Compound and Protein
Compound Name
4-[4-(6-amino-2-methylpyrimidin-4-yl)oxypiperidine-1-carbonyl]benzenesulfonyl fluoride
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PubChem ID
CID: 145975108
Canonical SMILES
Cc1nc(N)cc(OC2CCN(CC2)C(=O)c2ccc(cc2)S(F)(=O)=O)n1
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Compound Formula C17H19FN4O4S
Compound Structure
Protein Name
Lethal factor
Protein Classification
Enzyme
>
Protease
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Metallo protease
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Metallo protease MAE clan
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Metallo protease M34 family
Uniprot ID
P15917
Gene Name
LEF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  1
1
EC50 = 31.7 nM
   TI
   LI
   LO
   TS