Brief Information of the Compound and Protein
Compound Name
4-[[4-(4-amino-6-methylpyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]methyl]benzenesulfonyl fluoride
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PubChem ID
CID: 145964588
Canonical SMILES
Cc1nc(N)c2cnn(C3CCN(Cc4ccc(cc4)S(F)(=O)=O)CC3)c2n1
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Compound Formula C18H21FN6O2S
Compound Structure
Protein Name
Lethal factor
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MAE clan
>
Metallo protease M34 family
Uniprot ID
P15917
Gene Name
LEF
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000014 RAW 264.7 Mus musculus (Mouse)  1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS