Brief Information of the Compound and Protein
Compound Name
3-[4-[[5-fluoro-2-(4-methylphenyl)phenyl]methoxy]phenyl]propanoic acid
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PubChem ID
CID: 57522038
SID: 137279604
Canonical SMILES
Cc1ccc(cc1)-c1ccc(F)cc1COc1ccc(CCC(O)=O)cc1
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Compound Formula C23H21FO3
Compound Structure
Protein Name
Free fatty acid receptor 4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
Q5NUL3
Gene Name
FFAR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 = 75.3 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 158.49 nM
   TI
   LI
   LO
   TS
CL000460 Flp-In-T-REx-293 Homo sapiens (Human)  1
1
EC50 = 95.5 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 43.65 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 471 nM