Brief Information of the Compound and Protein
Compound Name
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[2-(1-methylindol-3-yl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide
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PubChem ID
CID: 145977147
Canonical SMILES
COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1ccnc(n1)-c1cn(C)c2ccccc12
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Compound Formula C28H33N7O2
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P21860
Gene Name
ERBB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000324 NCI-H3255 Homo sapiens (Human)  1
1
IC50 = 36 nM
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