Brief Information of the Compound and Protein
Compound Name
1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-methoxypyrrolidin-1-yl]prop-2-en-1-one
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PubChem ID
CID: 71535003
SID: 163531485
Canonical SMILES
CO[C@H]1CN(C[C@@H]1COc1nc(Nc2cnn(C)c2)nc2[nH]cc(Cl)c12)C(=O)C=C
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Compound Formula C19H22ClN7O3
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P21860
Gene Name
ERBB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000324 NCI-H3255 Homo sapiens (Human)  1
1
IC50 = 21 nM
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