Brief Information of the Compound and Protein
Compound Name
Mavelertinib
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PubChem ID
CID: 91668194
Canonical SMILES
COc1nn(C)cc1Nc1nc(nc2n(C)cnc12)N1C[C@@H](F)[C@@H](C1)NC(=O)C=C
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Compound Formula C18H22FN9O2
Compound Structure
Protein Name
Receptor tyrosine-protein kinase erbB-3
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P21860
Gene Name
ERBB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000324 NCI-H3255 Homo sapiens (Human)  1
1
IC50 = 4 nM
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