Brief Information of the Compound and Protein
Compound Name
 Compound Info 
AVL-301
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 PubChem ID
CID: 57335384
SID: 136337802
Canonical SMILES
COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O
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Compound Formula C27H28F3N7O3
Compound Structure
Protein Name
 Protein Info 
Receptor tyrosine-protein kinase erbB-3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P21860
Gene Name
ERBB3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000324 NCI-H3255
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 46 nM
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