Brief Information of the Compound and Protein
Compound Name
1-N-[(2S)-1-[[(2S)-1-(benzylamino)-1-oxopropan-2-yl]amino]-4-(2,2-dimethylpropylamino)-1,4-dioxobutan-2-yl]-4-N-hydroxybenzene-1,4-dicarboxamide
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PubChem ID
CID: 134823859
Canonical SMILES
C[C@H](NC(=O)[C@H](CC(=O)NCC(C)(C)C)NC(=O)c1ccc(cc1)C(=O)NO)C(=O)NCc1ccccc1
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Compound Formula C27H35N5O6
Compound Structure
Protein Name
Proteasome subunit beta type-5
Protein Classification
Enzyme
>
Protease
>
Threonine protease
>
Threonine protease PBT clan
>
Threonine protease T1A subfamily
Uniprot ID
P28074
Gene Name
PSMB5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000018 HL-60 Homo sapiens (Human)  1
1
IC50 = 260 nM
   TI
   LI
   LO
   TS
CL000164 SEM Homo sapiens (Human)  1
1
IC50 = 394.2 nM
   TI
   LI
   LO
   TS
CL000165 SUP-B15 Homo sapiens (Human)  1
1
IC50 = 820.5 nM
   TI
   LI
   LO
   TS