Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-1,1- dioxido-2,3-dihydrobenzo[b]thiophen-5- yl)oxy)nicotinonitrile
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 PubChem ID
CID: 118183706
Canonical SMILES
OC1c2c(ccc(Oc3cncc(c3)C#N)c2C(F)F)S(=O)(=O)C1(F)F
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Compound Formula C15H8F4N2O4S
Compound Structure
Protein Name
 Protein Info 
Endothelial PAS domain-containing protein 1
Protein Classification
Transcription factor
Uniprot ID
Q99814
Gene Name
EPAS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000244 786-O
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 180 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 140 nM