Brief Information of the Compound and Protein
Compound Name
(1S)-4-(3-chloro-5-fluorophenoxy)-7-(difluoromethylsulfonyl)-2,3-dihydro-1H-inden-1-ol
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PubChem ID
CID: 122506390
Canonical SMILES
O[C@H]1CCc2c1c(ccc2Oc1cc(F)cc(Cl)c1)S(=O)(=O)C(F)F
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Compound Formula C16H12ClF3O4S
Compound Structure
Protein Name
Endothelial PAS domain-containing protein 1
Protein Classification
Transcription factor
Uniprot ID
Q99814
Gene Name
EPAS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000244 786-O Homo sapiens (Human)  1
1
EC50 = 2900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 460 nM