Brief Information of the Compound and Protein
Compound Name
2-(3-chloro-5-fluorophenoxy)-5-(trifluoromethylsulfonyl)benzonitrile
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PubChem ID
CID: 117947131
Canonical SMILES
Fc1cc(Cl)cc(Oc2ccc(cc2C#N)S(=O)(=O)C(F)(F)F)c1
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Compound Formula C14H6ClF4NO3S
Compound Structure
Protein Name
Endothelial PAS domain-containing protein 1
Protein Classification
Transcription factor
Uniprot ID
Q99814
Gene Name
EPAS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000244 786-O Homo sapiens (Human)  1
1
EC50 = 11600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34 nM