Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-((5-Chloropyridin-3-yl)oxy)-4-(difluoromethyl)- 2,2-difluoro-3-hydroxy-2,3- dihydrobenzo[b]thiophene 1,1-dioxide
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 PubChem ID
CID: 118183634
Canonical SMILES
OC1c2c(ccc(Oc3cncc(Cl)c3)c2C(F)F)S(=O)(=O)C1(F)F
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Compound Formula C14H8ClF4NO4S
Compound Structure
Protein Name
 Protein Info 
Endothelial PAS domain-containing protein 1
Protein Classification
Transcription factor
Uniprot ID
Q99814
Gene Name
EPAS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000244 786-O
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 630 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 350 nM