Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9884843, Compound 10
    Show/Hide
 PubChem ID
CID: 118183703
Canonical SMILES
OC1c2c(ccc(Oc3cc(F)cc(Cl)c3)c2C#N)S(=O)(=O)C1(F)F
    Show/Hide
Compound Formula C15H7ClF3NO4S
Compound Structure
Protein Name
 Protein Info 
Endothelial PAS domain-containing protein 1
Protein Classification
Transcription factor
Uniprot ID
Q99814
Gene Name
EPAS1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000244 786-O
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 9200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 49 nM