Brief Information of the Compound and Protein
Compound Name
(1R,4aR,5S,6R,8aS)-5-[(2E)-2-[(4S)-4-[tert-butyl(dimethyl)silyl]oxy-2-oxooxolan-3-ylidene]ethyl]-1-(hydroxymethyl)-1,4a-dimethylspiro[3,4,5,7,8,8a-hexahydronaphthalene-6,2'-oxirane]-2-one
    Show/Hide
PubChem ID
CID: 145951232
Canonical SMILES
CC(C)(C)[Si](C)(C)O[C@@H]1COC(=O)\C1=C\C[C@@H]1[C@@]2(CO2)CC[C@@H]2[C@](C)(CO)C(=O)CC[C@@]12C
    Show/Hide
Compound Formula C26H42O6Si
Compound Structure
Protein Name
Signal transducer and activator of transcription 3
Protein Classification
Transcription factor
Uniprot ID
P40763
Gene Name
STAT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293 Homo sapiens (Human)  3
1
EC50 = 3950 nM
   TI
   LI
   LO
   TS
2
EC50 = 5990 nM
   TI
   LI
   LO
   TS
3
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 5900 nM
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
   TI
   LI
   LO
   TS