Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3E,4S)-3-[2-[(1S,2S,4aS,5R,6R,8aR)-6-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-5,8a-dimethylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]ethylidene]-4-hydroxyoxolan-2-one
    Show/Hide
 PubChem ID
CID: 145950701
Canonical SMILES
CC(C)(C)[Si](C)(C)O[C@@H]1CC[C@@]2(C)[C@H](C\C=C3/[C@H](O)COC3=O)[C@]3(CO3)CC[C@@H]2[C@]1(C)CO
    Show/Hide
Compound Formula C26H44O6Si
Compound Structure
Protein Name
 Protein Info 
Signal transducer and activator of transcription 3
Protein Classification
Transcription factor
Uniprot ID
P40763
Gene Name
STAT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 4160 nM
   TI
   LI
   LO
   TS
2
EC50 = 5390 nM
   TI
   LI
   LO
   TS
3
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 6150 nM
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
   TI
   LI
   LO
   TS