Brief Information of the Compound and Protein
Compound Name
[(1R,4aR,5S,6R,8aS)-5-[(2E)-2-[(4S)-4-[tert-butyl(dimethyl)silyl]oxy-2-oxooxolan-3-ylidene]ethyl]-1,4a-dimethyl-2-oxospiro[3,4,5,7,8,8a-hexahydronaphthalene-6,2'-oxirane]-1-yl]methyl acetate
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PubChem ID
CID: 145954862
Canonical SMILES
CC(=O)OC[C@@]1(C)[C@H]2CC[C@]3(CO3)[C@@H](C\C=C3/[C@@H](COC3=O)O[Si](C)(C)C(C)(C)C)[C@]2(C)CCC1=O
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Compound Formula C28H44O7Si
Compound Structure
Protein Name
Signal transducer and activator of transcription 3
Protein Classification
Transcription factor
Uniprot ID
P40763
Gene Name
STAT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293 Homo sapiens (Human)  2
1
EC50 = 5380 nM
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 8340 nM
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
   TI
   LI
   LO
   TS