Brief Information of the Compound and Protein
Compound Name
(3E,4S)-3-[2-[(1R,4aS,5R,8aS)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-5,8a-dimethyl-2-methylidene-6-oxo-1,3,4,4a,7,8-hexahydronaphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one
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PubChem ID
CID: 145949658
Canonical SMILES
CC(C)(C)[Si](C)(C)OC[C@@]1(C)[C@H]2CCC(=C)[C@@H](C\C=C3/[C@H](O)COC3=O)[C@]2(C)CCC1=O
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Compound Formula C26H42O5Si
Compound Structure
Protein Name
Signal transducer and activator of transcription 3
Protein Classification
Transcription factor
Uniprot ID
P40763
Gene Name
STAT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293 Homo sapiens (Human)  3
1
EC50 = 3450 nM
   TI
   LI
   LO
   TS
2
EC50 = 6450 nM
   TI
   LI
   LO
   TS
3
EC50 = 7750 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 8810 nM
   TI
   LI
   LO
   TS
2
EC50 = 8950 nM
   TI
   LI
   LO
   TS