Brief Information of the Compound and Protein
Compound Name
(3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-[tert-butyl(dimethyl)silyl]oxyoxolan-2-one
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PubChem ID
CID: 145962477
Canonical SMILES
CC(C)(C)[Si](C)(C)O[C@@H]1COC(=O)\C1=C\C[C@@H]1C(=C)CC[C@@H]2[C@](C)(CO)[C@H](O)CC[C@@]12C
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Compound Formula C26H44O5Si
Compound Structure
Protein Name
Signal transducer and activator of transcription 3
Protein Classification
Transcription factor
Uniprot ID
P40763
Gene Name
STAT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293 Homo sapiens (Human)  3
1
EC50 = 5680 nM
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
   TI
   LI
   LO
   TS
3
EC50 = 10570 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 6570 nM
   TI
   LI
   LO
   TS
2
EC50 > 10000 nM
   TI
   LI
   LO
   TS