Brief Information of the Compound and Protein
Compound Name
[(3S,4E)-4-[2-[(1R,4aS,5R,8aS)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-5,8a-dimethyl-2-methylidene-6-oxo-1,3,4,4a,7,8-hexahydronaphthalen-1-yl]ethylidene]-5-oxooxolan-3-yl] acetate
    Show/Hide
PubChem ID
CID: 145956215
Canonical SMILES
CC(=O)O[C@@H]1COC(=O)\C1=C\C[C@@H]1C(=C)CC[C@@H]2[C@](C)(CO[Si](C)(C)C(C)(C)C)C(=O)CC[C@@]12C
    Show/Hide
Compound Formula C28H44O6Si
Compound Structure
Protein Name
Signal transducer and activator of transcription 3
Protein Classification
Transcription factor
Uniprot ID
P40763
Gene Name
STAT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293 Homo sapiens (Human)  3
1
EC50 = 990 nM
   TI
   LI
   LO
   TS
2
EC50 = 1970 nM
   TI
   LI
   LO
   TS
3
EC50 = 7520 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 4430 nM
   TI
   LI
   LO
   TS
2
EC50 = 4570 nM
   TI
   LI
   LO
   TS