Brief Information of the Compound and Protein
Compound Name
[(3R,4E)-4-[2-[(1R,4aS,5R,6R,8aS)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-6-hydroxy-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-5-oxooxolan-3-yl] acetate
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PubChem ID
CID: 145958784
Canonical SMILES
CC(=O)O[C@H]1COC(=O)\C1=C\C[C@@H]1C(=C)CC[C@@H]2[C@](C)(CO[Si](C)(C)C(C)(C)C)[C@H](O)CC[C@@]12C
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Compound Formula C28H46O6Si
Compound Structure
Protein Name
Signal transducer and activator of transcription 3
Protein Classification
Transcription factor
Uniprot ID
P40763
Gene Name
STAT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000192 AD-293 Homo sapiens (Human)  3
1
EC50 = 3220 nM
   TI
   LI
   LO
   TS
2
EC50 = 7280 nM
   TI
   LI
   LO
   TS
3
EC50 = 8150 nM
   TI
   LI
   LO
   TS
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 9430 nM
   TI
   LI
   LO
   TS
2
EC50 = 9960 nM
   TI
   LI
   LO
   TS