Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[6-[2-(dimethylamino)ethyl-methylamino]pyridin-3-yl]-7-fluoro-1-(3-methoxycyclobutyl)-3-methylimidazo[4,5-c]quinolin-2-one
    Show/Hide
Canonical SMILES
CO[C@H]1C[C@H](C1)n1c2c(cnc3cc(F)c(cc23)-c2ccc(nc2)N(C)CCN(C)C)n(C)c1=O
    Show/Hide
Compound Formula C26H31FN6O2
Compound Structure
Protein Name
 Protein Info 
Serine-protein kinase ATM
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
Q13315
Gene Name
ATM
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 230 nM
   TI
   LI
   LO
   TS