Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(3-bromophenyl)-1,3-dihydro-[1]benzofuro[3,2-e][1,4]diazepin-2-one
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 PubChem ID
CID: 9841560
SID: 14803133
Canonical SMILES
Brc1cccc(c1)C1=NCC(=O)Nc2c1oc1ccccc21
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Compound Formula C17H11BrN2O2
Compound Structure
Protein Name
 Protein Info 
P2X purinoceptor 4
Protein Classification
Ion channel
>
Ligand-gated ion channel
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P2X receptor
Uniprot ID
Q99571
Gene Name
P2RX4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1
 Cell Line Info 
Homo sapiens (Human)  4
1
IC50 = 348 nM
   TI
   LI
   LO
   TS
2
IC50 = 350 nM
   TI
   LI
   LO
   TS
3
IC50 = 500 nM
   TI
   LI
   LO
   TS
4
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 3710 nM
   TI
   LI
   LO
   TS
2
IC50 = 3990 nM
   TI
   LI
   LO
   TS