Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-N-(3-methoxyphenyl)-2-[3-(trifluoromethyl)phenyl]quinazoline-4,6-diamine
    Show/Hide
 PubChem ID
CID: 145954560
Canonical SMILES
COc1cccc(Nc2nc(nc3ccc(N)cc23)-c2cccc(c2)C(F)(F)F)c1
    Show/Hide
Compound Formula C22H17F3N4O
Compound Structure
Protein Name
 Protein Info 
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4
 Cell Line Info 
Trichoplusia ni (Cabbage looper)  1
1
EC50 = 1230 nM
   TI
   LI
   LO
   TS
CL000036 MDCK-II
 Cell Line Info 
Canis lupus familiaris (Dog)  1
1
IC50 = 835 nM
   TI
   LI
   LO
   TS