Brief Information of the Compound and Protein
Compound Name
3-[[6-nitro-2-[3-(trifluoromethyl)phenyl]quinazolin-4-yl]amino]phenol
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PubChem ID
CID: 145954340
Canonical SMILES
Oc1cccc(Nc2nc(nc3ccc(cc23)[N+]([O-])=O)-c2cccc(c2)C(F)(F)F)c1
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Compound Formula C21H13F3N4O3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
EC50 = 21.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 27.6 nM
   TI
   LI
   LO
   TS