Brief Information of the Compound and Protein
Compound Name
3-[(6-nitro-2-pyridin-4-ylquinazolin-4-yl)amino]benzonitrile
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PubChem ID
CID: 145957857
Canonical SMILES
[O-][N+](=O)c1ccc2nc(nc(Nc3cccc(c3)C#N)c2c1)-c1ccncc1
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Compound Formula C20H12N6O2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  2
1
EC50 = 48.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 63.8 nM
   TI
   LI
   LO
   TS