Brief Information of the Compound and Protein
Compound Name
3-[[6-amino-2-[3-(trifluoromethyl)phenyl]quinazolin-4-yl]amino]phenol
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PubChem ID
CID: 145951213
Canonical SMILES
Nc1ccc2nc(nc(Nc3cccc(O)c3)c2c1)-c1cccc(c1)C(F)(F)F
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Compound Formula C21H15F3N4O
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 799 nM
   TI
   LI
   LO
   TS