Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,3S,4S,5S)-3-tert-butyl-4-[(5-tert-butyl-2-methoxyphenyl)methylamino]-1-(cyclohexanecarbonyl)-5-[2-(dimethylamino)pyridin-3-yl]pyrrolidine-2-carboxylic acid
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 PubChem ID
CID: 140859344
Canonical SMILES
COc1ccc(cc1CN[C@@H]1[C@@H](N([C@@H]([C@H]1C(C)(C)C)C(O)=O)C(=O)C1CCCCC1)c1cccnc1N(C)C)C(C)(C)C
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Compound Formula C35H52N4O4
Compound Structure
Protein Name
 Protein Info 
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
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Other ion channel
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Chloride channel
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Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o-
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 < 1000 nM
   TI
   LI
   LO
   TS