Brief Information of the Compound and Protein
Compound Name
3-[2-(2,2-dimethylpropanoylamino)-4-methyl-1,3-thiazol-5-yl]-N-(4-methoxyphenyl)-5-prop-2-enylpyrazole-1-carboxamide
    Show/Hide
PubChem ID
CID: 145953587
Canonical SMILES
COc1ccc(NC(=O)n2nc(cc2CC=C)-c2sc(NC(=O)C(C)(C)C)nc2C)cc1
    Show/Hide
Compound Formula C23H27N5O3S
Compound Structure
Protein Name
Cystic fibrosis transmembrane conductance regulator
Protein Classification
Ion channel
>
Other ion channel
>
Chloride channel
>
Cystic fibrosis transmembrane conductance regulator
Uniprot ID
P13569
Gene Name
CFTR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000535 CFBE41o- Homo sapiens (Human)  1
1
EC50 = 933.25 nM
   TI
   LI
   LO
   TS