Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)isoquinoline-3-carboxamide
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 PubChem ID
CID: 1345
SID: 14900970
Canonical SMILES
CCC(C)N(C)C(=O)c1cc2ccccc2c(n1)-c1ccccc1Cl
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Compound Formula C21H21ClN2O
Compound Structure
Protein Name
 Protein Info 
Translocator protein
Protein Classification
Membrane receptor
Uniprot ID
P30536
Gene Name
TSPO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 29.2 nM
   TI
   LI
   LO
   TS
2
Ki = 36 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 36 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Activity = 0.63 nM
2 IC50 = 1.1 nM
3 IC50 = 2.5 nM
4 IC50 = 490 nM
5 Kd = 2 nM
6 Kd = 11.1 nM
7 Ki = 2.3 nM
8 Ki = 4.5 nM
9 Ki = 7.11 nM