Brief Information of the Compound and Protein
Compound Name
3-[4-(3-hydroxy-4-methoxyanilino)quinazolin-2-yl]benzonitrile
    Show/Hide
PubChem ID
CID: 145974543
Canonical SMILES
COc1ccc(Nc2nc(nc3ccccc23)-c2cccc(c2)C#N)cc1O
    Show/Hide
Compound Formula C22H16N4O2
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 297 nM
   TI
   LI
   LO
   TS