Brief Information of the Compound and Protein
Compound Name
18beta-glycyrrhetic acid
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PubChem ID
CID: 10114
SID: 12015480
Canonical SMILES
CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O
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Compound Formula C30H46O4
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase type 2
Protein Classification
Enzyme
Uniprot ID
P80365
Gene Name
HSD11B2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.3 nM
   TI
   LI
   LO
   TS
3
IC50 = 257 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.22 nM