Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide
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 PubChem ID
CID: 57664406
Canonical SMILES
CN1CCN(CC1)C(=O)COc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl
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Compound Formula C19H24ClN5O3S
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08172
Gene Name
CHRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000845 CHO-K9
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  7
1
IC50 > 31622.78 nM
   TI
   LI
   LO
   TS
2
Kd = 3548.13 nM
   TI
   LI
   LO
   TS
3
Ki = 3548.13 nM
   TI
   LI
   LO
   TS
4
Ki = 5495.41 nM
   TI
   LI
   LO
   TS
5
Ki = 6456.54 nM
   TI
   LI
   LO
   TS
6
Ki = 9120.11 nM
   TI
   LI
   LO
   TS
7
Ki = 9332.54 nM
   TI
   LI
   LO
   TS