Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[1-[4-[1-[2-oxo-2-(6-oxo-5H-benzo[b][1,4]benzodiazepin-11-yl)ethyl]piperidin-4-yl]butyl]imidazol-4-yl]-N-[2-(propanoylamino)ethyl]propanamide
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 PubChem ID
CID: 122203596
Canonical SMILES
[3H]CC([3H])C(=O)NCCNC(=O)CCc1cn(CCCCC2CCN(CC(=O)N3c4ccccc4NC(=O)c4ccccc34)CC2)cn1
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Compound Formula C35H45N7O4
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08172
Gene Name
CHRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000845 CHO-K9
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 0.7586 nM
   TI
   LI
   LO
   TS
2
Ki = 1.096 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 33.88 nM
   TI
   LI
   LO
   TS
2
IC50 = 85.11 nM
   TI
   LI
   LO
   TS
3
IC50 = 354.81 nM
   TI
   LI
   LO
   TS