Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N1,N3-Bis(2-(3-(1-(4-(1-(2-oxo-2-(11-oxo-10,11-dihydro-5Hdibenzo[b,e][1,4]diazepin-5-yl)ethyl)piperidin-4-yl)butyl)-1H-imidazol-4-yl)propanamido)ethyl)-5-(propionamidomethyl)-isophthalamide Tetrakis(hydrotrifluoroacetate)
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 PubChem ID
CID: 137661317
Canonical SMILES
CCC(=O)NCc1cc(C(=O)NCCNC(=O)CCc2cn(CCCCC3CCN(CC(=O)N4c5ccccc5NC(=O)c5ccccc54)CC3)cn2)cc(C(=O)NCCNC(=O)CCc2cn(CCCCC3CCN(CC(=O)N4c5ccccc5NC(=O)c5ccccc54)CC3)cn2)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F
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Compound Formula C84H95F12N15O17
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P08172
Gene Name
CHRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000845 CHO-K9
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 0.1072 nM
   TI
   LI
   LO
   TS
2
Ki = 0.4074 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 16.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 173.78 nM
   TI
   LI
   LO
   TS
3
IC50 = 263.03 nM
   TI
   LI
   LO
   TS