Brief Information of the Compound and Protein
Compound Name
AVL-301
    Show/Hide
PubChem ID
CID: 57335384
SID: 136337802
Canonical SMILES
COc1cc(ccc1Nc1ncc(c(Nc2cccc(NC(=O)C=C)c2)n1)C(F)(F)F)N1CCN(CC1)C(C)=O
    Show/Hide
Compound Formula C27H28F3N7O3
Compound Structure
Protein Name
Insulin receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P06213
Gene Name
INSR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 190 nM
   TI
   LI
   LO
   TS