Brief Information of the Compound and Protein
Compound Name
(R)-1-(3-(4-Amino-3-(3-chloro-4-((3-(methylsulfonyl)benzyl)oxy)-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one
    Show/Hide
PubChem ID
CID: 130203752
Canonical SMILES
C=CC(=O)N1CCC[C@@H](n2nc(-c3ccc(OCc4cccc(S(C)(=O)=O)c4)c(Cl)c3)c3c(N)ncnc32)C1
    Show/Hide
Compound Formula C27H27ClN6O4S
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 1000 nM
   TI
   LI
   LO
   TS