Brief Information of the Compound and Protein
Compound Name
(R)-5-(1-(1-Acryloylpiperidin-3-yl)-4-amino-1H-pyrazolo[3,4-d]-pyrimidin-3-yl)-2-(pyridin-2-ylmethoxy)benzonitrile
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PubChem ID
CID: 130203349
Canonical SMILES
C=CC(=O)N1CCC[C@@H](n2nc(-c3ccc(OCc4ccccn4)c(C#N)c3)c3c(N)ncnc32)C1
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Compound Formula C26H24N8O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 2200 nM
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