Brief Information of the Compound and Protein
Compound Name
1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
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PubChem ID
CID: 14925759
Canonical SMILES
O=C1CCc2ccccc2N1CCCN1CCN(CC1)c1ccccc1
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Compound Formula C22H27N3O
Compound Structure
Protein Name
Muscarinic acetylcholine receptor M1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Acetylcholine receptor
Uniprot ID
P11229
Gene Name
CHRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 4265.8 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T Homo sapiens (Human)  2
1
EC50 = 645.65 nM
   TI
   LI
   LO
   TS
2
IC50 = 831.76 nM
   TI
   LI
   LO
   TS