Brief Information of the Compound and Protein
Compound Name
N-(3,4-dimethoxyphenyl)-2-(3-methoxyphenyl)pyrido[2,3-d]pyrimidin-4-amine
    Show/Hide
PubChem ID
CID: 137641058
Canonical SMILES
COc1cccc(c1)-c1nc(Nc2ccc(OC)c(OC)c2)c2cccnc2n1
    Show/Hide
Compound Formula C22H20N4O3
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 572 nM
   TI
   LI
   LO
   TS