Brief Information of the Compound and Protein
Compound Name
4-[[2-(3-methoxyphenyl)pyrido[2,3-d]pyrimidin-4-yl]amino]benzonitrile
    Show/Hide
PubChem ID
CID: 137640534
Canonical SMILES
COc1cccc(c1)-c1nc(Nc2ccc(cc2)C#N)c2cccnc2n1
    Show/Hide
Compound Formula C21H15N5O
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 876 nM
   TI
   LI
   LO
   TS