Brief Information of the Compound and Protein
Compound Name
(2S)-2-cyclopropyl-N-[(6S)-5,11-dioxospiro[3,6-dihydro-1H-pyrazolo[1,2-b][2,3]benzodiazepine-2,1'-cyclopropane]-6-yl]-N'-(5-fluoro-2-methylpyridin-3-yl)butanediamide
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PubChem ID
CID: 134691740
Canonical SMILES
Cc1ncc(F)cc1NC(=O)C[C@@H](C1CC1)C(=O)N[C@H]1c2ccccc2C(=O)N2CC3(CC3)CN2C1=O
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Compound Formula C27H28FN5O4
Compound Structure
Protein Name
Signal peptide peptidase-like 2A
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9JJF9
Gene Name
SPPL2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000160 A20 Mus musculus (Mouse)  1
1
IC50 = 137 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS