Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[2,2-dimethylpropyl-[[4-[3-(4-propan-2-ylpiperazin-1-yl)prop-1-ynyl]phenyl]methyl]amino]pyrimidine-2-carbonitrile
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 PubChem ID
CID: 10003594
SID: 14983443
Canonical SMILES
CC(C)N1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1
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Compound Formula C27H36N6
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 4
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
P46093
Gene Name
GPR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 < 23000 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1930 nM
   TI
   LI
   LO
   TS