Brief Information of the Compound and Protein
Compound Name
VORAPAXAR
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PubChem ID
CID: 10077130
SID: 81044371
Canonical SMILES
CCOC(=O)N[C@@H]1CC[C@@H]2[C@@H](C1)C[C@H]1C(=O)O[C@H](C)[C@H]1[C@H]2/C=C/c1ccc(-c2cccc(F)c2)cn1
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Compound Formula C29H33FN2O4
Compound Structure
Protein Name
Proteinase-activated receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Protease-activated receptor
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Protease-activated receptor
Uniprot ID
P25116
Gene Name
F2R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 64 nM
   TI
   LI
   LO
   TS
CL000667 KNRK Rattus norvegicus (Rat)  1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS