Brief Information of the Compound and Protein
Compound Name
2-amino-4-[4-(hydroxymethyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
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PubChem ID
CID: 129320519
Canonical SMILES
Nc1nc(-c2ccc(CO)cc2)c2c(c[nH]c2n1)C#N
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Compound Formula C14H11N5O
Compound Structure
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit alpha
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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Other protein kinase group
Uniprot ID
O15111
Gene Name
CHUK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 13900 nM
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