Brief Information of the Compound and Protein
Compound Name
4-(2-amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-4-yl)benzenesulfonamide
    Show/Hide
PubChem ID
CID: 137641677
Canonical SMILES
Nc1nc(-c2ccc(cc2)S(N)(=O)=O)c2c(c[nH]c2n1)C#N
    Show/Hide
Compound Formula C13H10N6O2S
Compound Structure
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit alpha
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
Uniprot ID
O15111
Gene Name
CHUK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 5800 nM
   TI
   LI
   LO
   TS