Brief Information of the Compound and Protein
Compound Name
6-[(1-methylpyrazol-3-yl)amino]-4-(2-methylpyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
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PubChem ID
CID: 137636896
Canonical SMILES
Cc1cc(ccn1)-c1cc(Nc2ccn(C)n2)nc2[nH]cc(C#N)c12
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Compound Formula C18H15N7
Compound Structure
Protein Name
Leucine-rich repeat serine/threonine-protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase LRRK family
Uniprot ID
Q5S007
Gene Name
LRRK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
2
IC50 = 700 nM
   TI
   LI
   LO
   TS