Brief Information of the Compound and Protein
Compound Name
8-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-2-(1-methyl-2-oxopyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one
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PubChem ID
CID: 137633091
Canonical SMILES
Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CCN(C2=O)c2ccn(C)c(=O)c2)CC1
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Compound Formula C25H29N3O5
Compound Structure
Protein Name
ATP-sensitive inward rectifier potassium channel 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Inwardly rectifying potassium channel
Uniprot ID
P48048
Gene Name
KCNJ1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 7600 nM
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