Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(3-chloro-5-fluoropyridin-4-yl)-7-[2-[2-chloro-4-(trifluoromethyl)phenyl]ethynyl]-4,4-dimethyl-3H-chromeno[3,4-d]imidazole
    Show/Hide
 PubChem ID
CID: 137648374
Canonical SMILES
CC1(C)Oc2cc(ccc2-c2nc([nH]c12)-c1c(F)cncc1Cl)C#Cc1ccc(cc1Cl)C(F)(F)F
    Show/Hide
Compound Formula C26H15Cl2F4N3O
Compound Structure
Protein Name
 Protein Info 
Prostaglandin E synthase
Protein Classification
Enzyme
>
Isomerase
Uniprot ID
O14684
Gene Name
PTGES
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 73.89 nM
   TI
   LI
   LO
   TS